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Vendsyssel come into this on the back of a heavy home defeat, which will have stung, but they remain a solid Danish second-tier outfit with genuine home pedigree at Hjørring. Hillerød, meanwhile, could only manage a draw at home against Aarhus Fremad, suggesting they lack the cutting edge to impose themselves on the road. The market prices this as a tight contest, yet Vendsyssel's superior squad depth and the need to respond after a poor result give them the edge. Expect a cautious opening, but the home side's urgency should tell in the second half.

Egnatia produced a stunning 5-1 win over Shamrock Rovers in the previous round, but that result flattered a side that otherwise lacks European pedigree at this level. Lillestrøm, despite a recent league defeat to Rosenborg, are a far more established outfit with superior individual quality across the pitch. The Norwegian side will be organised, patient and dangerous on the break, exactly the profile that troubles Albanian sides. Egnatia's aggressive, direct approach may create chances, but Lillestrøm's defensive solidity and counter-attacking threat should see them edge a tight first leg.

OFI arrive on a wave of cup success and a Super Cup triumph, giving them genuine belief in this first European tie for years. CSKA Sofia, however, are in formidable form domestically, having thrashed Botev Vratsa 5-0, and possess a settled, experienced side led by captain Bruno Jordao. With both teams confident and the first leg likely to be tight and tactical, a draw is a strong possibility. OFI's home crowd will drive them forward, but CSKA's organised 5-3-2 shape is built to frustrate and nick something on the road.

Lugano have started the Swiss season in explosive fashion, dismantling Zürich 5-0 in their most recent outing, and they carry that firepower into this Conference League playoff. Maccabi Tel Aviv, by contrast, have been hit by a raft of injuries and absences, leaving their squad depleted and their rhythm disrupted. The Swiss side's 3-4-2-1 system, with Renato Steffen and Dereck Moncada pulling the strings, should overwhelm a Maccabi side that has struggled for consistency. Home advantage at the AIL Arena, combined with Maccabi's travel and squad issues, points firmly to a Lugano win.

Bastia, back in the third tier after a tough Ligue 2 campaign, will be desperate to make Furiani a fortress again. Their recent defeat to Le Puy was a setback, but the passionate home support should lift them against a Versailles side that is still finding its feet, especially with key attacker Bilal Cissé sidelined through injury. Versailles have shown resilience with a narrow win over Le Puy, but their away form and lack of firepower without Cissé are concerns. Bastia's physical, direct style, tailored for home advantage, should grind out a result.

Bourg-Péronnas secured a hard-fought 3-2 win over Villefranche, showing attacking intent but also defensive fragility. Thionville, though less well-known, come into this as a side with momentum and a more settled squad, and the odds reflect a genuine belief they can take something. The home side's open style leaves gaps at the back, which Thionville's pace on the counter can exploit. With both teams likely to score, the away side's greater efficiency in front of goal should prove decisive in a tight contest.

Fleury Mérogis, though a less established name, have home advantage and a point to prove in the French third tier. Orléans, with their longer history, are the more recognisable side but have shown inconsistency, managing only a narrow friendly win over Paris 13. The market prices this as a close game, but Fleury's energy and directness at home could unsettle an Orléans side that often struggles on the road. Expect a scrappy, competitive match where the home side's intensity edges it.

La Rochelle, playing at home, have shown a tendency for high-scoring games, with both teams scoring in all their home matches so far. Cannes, despite their historical name, are a side in transition and have struggled for consistency. The home side's attacking intent, combined with Cannes' defensive frailties, suggests goals, but La Rochelle's ability to outscore opponents at home should give them the edge. The market sees this as close, but home advantage and a more direct style should see La Rochelle through.

Le Puy, despite a recent defeat to Bastia, have shown they can compete at this level and will be buoyed by home support. Amiens, a side with Ligue 2 pedigree, are expected to be strong, but their away form has been inconsistent. The market prices this as a close game, but Le Puy's direct, physical approach at home could unsettle Amiens. With both teams likely to create chances, the home side's determination and familiarity with their pitch should give them a slight edge.

Paris 13 Atletico are a newly established side in the third tier, and their lack of experience at this level shows in the odds. Valenciennes, a club with significant Ligue 2 history, are strong favourites and will be eager to assert their superiority. The away side's superior squad depth and tactical organisation should prove too much for the hosts. Valenciennes' recent form, including a solid start, suggests they will control the game and come away with a comfortable win.

Hearts have found a new lease of life recently, with an upturn in results boosting confidence ahead of this Conference League playoff. Playing at the intimidating Tynecastle Park, they will be eager to secure a first-leg advantage. Rapid Vienna, though a historically strong Austrian side, have been inconsistent and may struggle with the hostile atmosphere. Hearts' physical, high-energy style, tailored for European nights at home, should give them the edge in a tight contest.

Sheffield Wednesday have started the season with two wins and two clean sheets, and they now face their first home league game in front of a massive Hillsborough crowd. Bradford City, despite their own strong start, are yet to play away this season and lost 10 of their 23 road games last term. The Owls' home advantage, combined with their defensive solidity and the creative influence of Barry Bannan, should prove decisive. Bradford's attacking threat is real, but Wednesday's organisation and momentum should see them through.

Rayo Vallecano are looking to bounce back from an opening-day defeat, and they will be eager to use home advantage at Vallecas to get their season going. Alaves, however, have won four in a row, including a 3-0 thrashing of Getafe, and will be full of confidence. This is a classic clash between a desperate home side and an in-form away team. The market sees it as close, and with both sides having strengths, a draw is a very plausible outcome. Rayo's attacking intent will be met by Alaves' solid defensive structure.

Dinamo Tirana have been free-scoring in Europe, but their inconsistency is a concern, and they face a Pafos side that dismantled Hajduk Split 4-0 in their last European outing. Pafos have a more settled attacking core and recent European experience, which should prove decisive. The Cypriot side's superior quality and organisation, combined with Dinamo's defensive vulnerabilities, point to an away win. Despite the home side's goal threat, Pafos' efficiency in front of goal should see them edge a high-scoring first leg.

Hajduk Split are in red-hot form, having scored 14 goals in their recent five games, with Michele Šego netting four. They are at home and have avoided being behind at half-time in 18 of their last 20 matches, showing they start strongly. Raków, though a solid Polish side, have been less convincing and will struggle to contain Hajduk's attacking firepower. The home side's momentum and the intimidating atmosphere at Poljud should see them take control of this first leg. Expect Hajduk to dominate possession and create numerous chances.

Shamrock Rovers are the Irish champions and have a formidable home record at Tallaght Stadium, where they are notoriously tough to beat. KuPS, the Finnish champions, are a solid side but have struggled away from home in Europe. The return of Gustav Engvall adds experience to KuPS, but Shamrock's attacking options and the backing of a passionate home crowd should prove decisive. Expect a tight, competitive first leg, but Shamrock's home advantage and European pedigree should see them edge it.