Venezia are expected to line up in a 3-5-2, with Stankovic in goal behind a back three of Schingtienne, Moreno, and Juan Jesus. The wing-backs, Hainaut and Haps, will need to provide width, but they also have to track back diligently against Lazio's wide forwards. In midfield, Kike Perez, Basic, and Sohm form a trio that must protect the defence and spring counterattacks. Up front, Yeboah and Adams will look to stretch the Lazio backline with runs in behind. The system relies on compactness and quick transitions, but Venezia have struggled to maintain that discipline for 90 minutes.

Lazio are likely to set up in a 4-3-3, with Mandas in goal and a back four of Floriani Mussolini, Sutalo, Provstgaard, and Tavares. The midfield three will likely include Frattesi, and they will look to dominate possession and dictate the tempo. Gattuso's side have the quality to knife through the lines, especially with Zaccagni's creativity and Dia's finishing. The key battle will be in the wide areas: Venezia's wing-backs against Lazio's attacking full-backs. If Lazio can pin Venezia back, the home side's back three will be stretched, and gaps will appear.