Newcastle host Liverpool in a marquee Premier League opener, with the visitors as clear favourites. Liverpool have a strong squad, with the predicted lineup featuring Alisson, van Dijk, and Wirtz, and they will be looking to start their title challenge strongly. Newcastle, meanwhile, have a solid squad but face a significant test against Liverpool's attacking quality. The market clearly favours Liverpool, and their away form has been strong in recent seasons. Newcastle will be competitive at St James' Park, but Liverpool's superior quality in midfield and attack should prove decisive. A draw is a possibility given the competitive nature of the fixture, but an away win is the most likely outcome.